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Anti -MEK1 Rabbit pAb

Cat. No. GB11600

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

MEK1 rabbit polyclonal

Protein full name

Dual specificity mitogen-activated protein kinase kinase 1

Synonyms

MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1, mitogen activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1

Immunogen

Recombinant protein corresponding to Mouse MEK1

Isotype IgG
Purity Affinity purification

Predicted MW.

43 kDa

Observed MW.

45 kDa
Uniprot ID P31938, Q02750, Q01986

 


 

Applications

 

 

Applications WB    
Species

Human, Mouse, Rat

   
Dilution

1: 500-1: 1000

   
Positive tissue Lung, kidney    

 


 

Background

 

Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme that in humans is encoded by the MAP2K1 gene. The protein encoded by this gene is a member of the dual-specificity protein kinase family that acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon activation by a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.       

     


 

Images

 

 

内页-1.jpg  

Western blot analysis of MEK1 (GB11600) at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: A431 cell lysate

Lane 4: NIH/3T3 cell lysate

Lane 5: PC12 cell lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Mouse kidney tissue lysate

Lane 8: Rat lung tissue lysate

Lane 9: Rat kidney tissue lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.