Chinese | English  
Servicebio

TEL

+86 (0) 27 5111 3188

Polyclonals

  1. Home
  2. Products
  3. Primary antibodies
  4. Polyclonals
  5. Content

Anti -DOK1 Rabbit pAb

Cat. No. GB11775

Brand:Servicebio

Price:230.00

Specification: 100μl

Download Attachment Files
Attachment Download Address: ×
/e/DownSys/DownSoft/?classid=19&id=469&pathid=0

Product Information

 

 

Description

DOK1 rabbit polyclonal

Protein full name

Docking protein 1

Synonyms

Dok1, DOK1, P62DOK, pp62, docking protein 1

Immunogen

Recombinant protein corresponding to Mouse DOK1

Isotype IgG
Purity Affinity purification
Predicted MW.

53 kDa

Observed MW.

62 kDa

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

Q99704, P97465, Q4QQV2

 


 

Applications

 

 

Applications

WB

   
Species

Human, Mouse, Rat

   
Dilution

1: 500-1: 1200

   
Positive tissue

Thymus, lung, kidney

   

 


 

Background

 

Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

             


 

Images

 

 

image.png  

Western blot analysis of DOK1 (GB11775) at dilution of 1: 1000

Lane 1: MCF7 cell lysate

Lane 2: Jurkat cell lysate

Lane 3: THP-1 cell lysate

Lane 4: Mouse thymus tissue lysate

Lane 5: Mouse lung tissue lysate

Lane 6: Mouse kidney tissue lysate

Lane 7: Rat thymus tissue lysate

Lane 8: Rat lung tissue lysate

Lane 9: Rat kidney tissue lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

 

No relevant information