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Anti -FIP200 Rabbit pAb

Cat. No. GB11774

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

FIP200 rabbit polyclonal

Protein full name

RB1-inducible coiled-coil protein 1

Synonyms

Rb1cc1, RB1CC1, ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1

Immunogen

Recombinant protein corresponding to Mouse FIP200

Isotype IgG
Purity Affinity purification

Predicted MW.

183 kDa

Observed MW.

183-200 kDa

Uniprot ID

Q8TDY2

 


 

Applications

 

 

Applications

WB

   
Species

Human

   
Dilution

1: 500-1: 1000

   
Positive tissue

Hela, MCF7, A20

   

 


 

Background

 

 

Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor, is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Involved in autophagy. Required for autophagosome formation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.

            


 

Images

 

 

image.png  

Western blot analysis of FIP200 (GB11774) at dilution of 1: 800

Lane 1: Hela cell lysate

Lane 2: MCF7 cell lysate

Lane 3: A20 cell lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.