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Anti -FIP200 Rabbit pAb

Cat. No. GB11774

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

Description FIP200 rabbit polyclonal
Protein full name RB1-inducible coiled-coil protein 1
Synonyms Rb1cc1, RB1CC1, ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1
Immunogen Recombinant protein corresponding to
Mouse FIP200
Isotype IgG
Purity Affinity purification
Predicted MW. 183 kDa
Observed MW. 183 kDa
Uniprot ID Q8TDY2

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Human 1: 500-1: 1000 Hela, MCF7, A20

 


 

Background

 

 

Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Involved in autophagy. Required for autophagosome formation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.

            


 

Images

 

 

image.png  

Western blot analysis of FIP200 (GB11774) at dilution of 1: 800

Lane 1: Hela cell lysate

Lane 2: MCF7 cell lysate

Lane 3: A20 cell lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.