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Anti -Ionotropic Glutamate receptor 2 Rabbit pAb

Cat. No. GB11770

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Ionotropic Glutamate receptor 2 rabbit polyclonal

Protein full name

Glutamate receptor 2

Synonyms

Gria2, GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2, glutamate ionotropic receptor AMPA type subunit 2

Immunogen

Recombinant protein corresponding to Mouse GRIA2

Isotype IgG
Purity Affinity purification
Subcellular location

Cell membran, Cytoplasm

Uniprot ID

P23819, P19491

 


 

Applications

 

 

Applications

IHC

IF

 
Species

Mouse, Rat

Mouse, Rat

 
Dilution

1: 500-1: 1000

1: 250-1: 500

 
Positive tissue

Brain

Brain

 

 


 

Background

 

Lonotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

             


 

Images

 

 

image.png  

Immunohistochemistry analysis of paraffin-embedded mouse brain using GRIA2 (GB11770) at dilution of 1: 500

     
image.png  

Immunohistochemistry analysis of paraffin-embedded rat brain using GRIA2 (GB11770) at dilution of 1: 500

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.