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Anti -IRF7 Rabbit pAb

Cat. No. GB111169

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

IRF7 rabbit polyclonal

Protein full name

Interferon regulatory factor 7

Synonyms

Irf7

Immunogen

Recombinant protein corresponding to Mouse IRF7

Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus, Cytoplasm

Uniprot ID

F7FGY2

 


 

Applications

 

Applications

IHC

IF

Species

Rat

Rat

Dilution

1: 1500-1: 3000

1: 1500-1: 3000

Positive tissue

liver, spleen, thymus

lung, liver, spleen, thymus

 


 

Background

 

IRF7 is the key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes and IFN-stimulated genes by binding to an interferon-stimulated response element  in their promoters. Can efficiently activate both the IFN-beta and the IFN-alpha genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway.Can also play a role in regulating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or through induction of IRF1. Binds to the Q promoter of EBV nuclear antigen 1 a and may play a role in the regulation of EBV latency. Can activate distinct gene expression programs in macrophages and regulate the anti-tumor properties of primary macrophages.
 


 

Images

 

Immunohistochemistry analysis of paraffin-embedded rat liver using IRF7 (GB111169) at dilution of 1: 2000

   

Immunohistochemistry analysis of paraffin-embedded rat spleen using IRF7 (GB111169) at dilution of 1: 2000

   

Immunohistochemistry analysis of paraffin-embedded rat thymus using IRF7 (GB111169) at dilution of 1: 2000

   

Immunofluorescent analysis of paraffin-embedded rat lung using IRF7 (GB111169) at dilution of 1: 2000

   

Immunofluorescent analysis of paraffin-embedded rat liver using IRF7 (GB111169) at dilution of 1: 2000

 
   

Immunofluorescent analysis of paraffin-embedded rat spleen using IRF7 (GB111169) at dilution of 1: 2000
 
   

Immunofluorescent analysis of paraffin-embedded rat thymus using IRF7 (GB111169) at dilution of 1: 2000
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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