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Anti -FABP-1 Rabbit pAb

Cat. No. GB111152

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

FABP-1 rabbit polyclonal

Protein full name Fatty acid-binding protein, liver
 

Synonyms

14 kDa selenium-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse FABP-1

Isotype IgG
Purity Affinity purification

Predicted MW.

14 kDa

Observed MW.

14 kDa

Uniprot ID

P12710, P02692

 


 

Applications

 

Applications

WB

Species

Mouse, Rat

Dilution

1: 300-1: 600

Positive tissue

liver

 


 

Background

 

Fatty acid binding proteins (FABP) are small intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellulair utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of ischemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.
 


 

Images

 

Western blot analysis of FABP-1 (GB111152) at dilution of 1: 600
Lane 1: Mouse liver tissue lysate
Lane 2: Rat liver tissue lysate
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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