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Anti -S100A9 Rabbit pAb

Cat. No. GB111149

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

S100A9 rabbit polyclonal

Protein full name Protein S100-A9
 

Synonyms

Calgranulin-B, Leukocyte L1 complex heavy chain, MRP-14, p14, S100 calcium-binding protein A9, S100a9, Cagb, Mrp14

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse S100A9

Isotype IgG
Purity Affinity purification
Subcellular location

Cytoplasm, Cell membrane, Secreted

Predicted MW.

13 kDa

Observed MW.

13 kDa

Uniprot ID

P31725, P50116

 


 

Applications

 

Applications

WB

IHC

IF

Species

Mouse, Rat

Mouse, Rat

Mouse, Rat

Dilution

1: 300-1: 800

1: 1500-1: 3000

1: 750-1: 1500

Positive tissue

spleen, lung

lung, liver, spleen, small intestine

lung, spleen

 


 

Background

 

Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
 


 

Images

 

Western blot analysis of S100A9 (GB111149) at dilution of 1: 800
Lane 1: Mouse spleen tissue lysate
Lane 2: Mouse lung tissue lysate
Lane 1: Rat spleen tissue lysate
Lane 2: Rat lung tissue lysate
 

   

Immunohistochemistry analysis of paraffin-embedded mouse lung using S100A9 (GB111149) at dilution of 1: 1800
 

   

Immunohistochemistry analysis of paraffin-embedded rat lung using S100A9 (GB111149) at dilution of 1: 1800
 

   

Immunohistochemistry analysis of paraffin-embedded mouse liver using S100A9 (GB111149) at dilution of 1: 1800
 

   


Immunohistochemistry analysis of paraffin-embedded rat liver using S100A9 (GB111149) at dilution of 1: 1800
 
   


Immunohistochemistry analysis of paraffin-embedded mouse spleen using S100A9 (GB111149) at dilution of 1: 1800
 
   

Immunohistochemistry analysis of paraffin-embedded rat spleen using S100A9 (GB111149) at dilution of 1: 1800
 
   

Immunohistochemistry analysis of paraffin-embedded rat small intestine using S100A9 (GB111149) at dilution of 1: 1800
 
   

Immunofluorescent analysis of paraffin-embedded mouse lung using S100A9 (GB111149) at dilution of 1: 1000
 
   

Immunofluorescent analysis of paraffin-embedded mouse spleen using S100A9 (GB111149) at dilution of 1: 1000
 
   

Immunofluorescent analysis of paraffin-embedded rat spleen using S100A9 (GB111149) at dilution of 1: 1000
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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