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Anti -ATF-4 Rabbit pAb

Cat. No. GB111137

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

ATF-4 rabbit polyclonal

Protein full name Cyclic AMP-dependent transcription factor ATF-4

Synonyms

cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, C/EBP-related ATF, C/ATF, TaxREB67 homolog, Atf4

Immunogen

Recombinant protein corresponding to Mouse ATF-4

Isotype IgG
Purity Affinity purification
Subcellular location

Cell membrane, Cytoplasm, Nucleus

Uniprot ID

P18848, Q06507, Q9ES19

 


 

Applications

 

Applications

IHC

IF

Species

Human, Mouse, Rat

Human, Mouse, Rat

Dilution

1: 1500-1: 3000

1: 1500-1: 3000

Positive tissue

colon, liver, brain,  small intestine, kidney

breast, liver, brain

 


 

Background

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
 

 


 

Images

 

Immunohistochemistry analysis of paraffin-embedded human colon using ATF-4 (GB111137) at dilution of 1: 1600
 

   

Immunohistochemistry analysis of paraffin-embedded mouse colon using ATF-4 (GB111137) at dilution of 1: 1600
 

   

Immunohistochemistry analysis of paraffin-embedded mouse brain using ATF-4 (GB111137) at dilution of 1: 1600
 

   

Immunohistochemistry analysis of paraffin-embedded mouse liver using ATF-4 (GB111137) at dilution of 1: 1600
 

   

Immunohistochemistry analysis of paraffin-embedded mouse small intestine using ATF-4 (GB111137) at dilution of 1: 1600

 
   

Immunohistochemistry analysis of paraffin-embedded rat kidney using ATF-4 (GB111137) at dilution of 1: 1600

 
   

Immunofluorescent analysis of paraffin-embedded human breast using ATF-4 (GB111137) at dilution of 1: 1500
 
   

Immunofluorescent analysis of paraffin-embedded mouse liver using ATF-4 (GB111137) at dilution of 1: 1500
 
   

Immunofluorescent analysis of paraffin-embedded rat brain using ATF-4 (GB111137) at dilution of 1: 1500
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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