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Anti -S6K1 Rabbit pAb

Cat. No. GB111133

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

S6K1 rabbit polyclonal

Protein full name

Ribosomal protein S6 kinase beta-1

Synonyms

S6K-beta-1, S6K1, P70S6K1, S6K, Ribosomal protein S6 kinase I, p70 S6 kinase alpha, Rps6kb1, 70 kDa ribosomal protein S6 kinase 1

Immunogen

Recombinant protein corresponding to Mouse S6K1

Isotype IgG
Purity Affinity purification

Predicted MW.

59 kDa

Observed MW.

70 kDa

Uniprot ID

P23443, Q8BSK8, P67999

 


 

Applications

 

Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

brain, testis

 


 

Background

 

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.

 


 

Images

 

Western blot analysis of S6K1 (GB111133) at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: PC12 cell lysate
Lane 3: MCF7 cell lysate
Lane 4: NIH/3T3 cell lysate
Lane 5: Mouse brain tissue lysate
Lane 6: Mouse testis tissue lysate
Lane 7: Rat brain tissue lysate
Lane 8: Rat testis tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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