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Anti -Cyclin A2 Rabbit pAb

Cat. No. GB111132

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

Cyclin A2 rabbit polyclonal

Protein full name

Cyclin-A2

Synonyms

Cyclin-A, Cyclin A, CCNA2, CCN1, CCNA

Immunogen

Recombinant protein corresponding to Human Cyclin A2

Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus

Predicted MW.

49 kDa

Observed MW.

55 kDa

Uniprot ID

P20248, P51943, G3V802

 


 

Applications

 

Applications

WB

IHC

IF

Species

Human, Mouse

Human, Mouse, Rat

Human, Mouse

Dilution

1: 500-1: 1000

1: 500-1: 1000

1: 250-1: 500

Positive tissue

lymph nodes, spleen

lymph nodes, brain, testis

lung cancer, kidney

 


 

Background

 

Cyclin A2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. Cyclin A2 binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Cyclin A2 could be phosphorylated during the G2/M.

 

 


 

Images

 

Western blot analysis of Cyclin A2 (GB111132) at dilution of 1: 1000
Lane 1: HCT116 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: HT29 cell lysate
Lane 4: K562 cell lysate
Lane 5: SW480 cell lysate
Lane 6: Mouse lymph nodes tissue lysate
Lane 7: Mouse spleen tissue lysate

   

Immunohistochemistry analysis of paraffin-embedded using human lymph nodes Cyclin A2 (GB111132) at dilution of 1: 1000

   

Immunohistochemistry analysis of paraffin-embedded using mouse brain Cyclin A2 (GB111132) at dilution of 1: 600

   

Immunohistochemistry analysis of paraffin-embedded using rat testis Cyclin A2 (GB111132) at dilution of 1: 600

   

Immunofluorescent analysis of paraffin-embedded using human lung cancer Cyclin A2 (GB111132) at dilution of 1: 500
 
   

Immunofluorescent analysis of paraffin-embedded using mouse kidney Cyclin A2 (GB111132) at dilution of 1: 500
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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