Chinese | English  
Servicebio

TEL

+86 (0) 27 5111 3188

Polyclonals

  1. Home
  2. Products
  3. Primary antibodies
  4. Polyclonals
  5. Content

Anti -SYT1 Rabbit pAb

Cat. No. GB111130

Brand:Servicebio

Price:230

Specification: 100μl

Download Attachment Files
Attachment Download Address: ×
/e/DownSys/DownSoft/?classid=19&id=3508&pathid=0

Product Information

 

Description

SYT1 rabbit polyclonal

Protein full name

Synaptotagmin-1 

Synonyms

Synaptotagmin I, SytI, p65, Syt1

Immunogen

Recombinant protein corresponding to Mouse SYT1

Isotype IgG
Purity Affinity purification
Subcellular location

Cell Membrane

Predicted MW.

47 kDa

Observed MW.

60 kDa

Uniprot ID

P21579, P46096, P21707

 


 

Applications

 

Applications

WB

IHC

Species

Mouse, Rat

Human

Dilution

1: 500-1: 1000

1: 1000-1: 2000

Positive tissue

brain, cortex, hippocampus

lung cancer

 


 

Background

 

This protein calcium sensor that participates in triggering neurotransmitter release at the synapse . May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.

 


 

Images

 

Western blot analysis of SYT1 (GB111130) at dilution of 1: 1000
Lane 1: Mouse brain tissue lysate
Lane 2: Mouse cortex tissue lysate
Lane 3: Mouse hippocampus tissue lysate
Lane 4: Rat brain tissue lysate
Lane 5: Rat cortex tissue lysate
Lane 6: Rat hippocampus tissue lysate

   

Immunohistochemistry analysis of paraffin-embedded human lung cancer using SYT1 (GB111130) at dilution of 1: 2000

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

No relevant information