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Anti -CITED2 Rabbit pAb

Cat. No. GB111129

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

CITED2 rabbit polyclonal

Protein full name

Cbp/p300-interacting transactivator 2

Synonyms

MSG-related protein 1, MRG-1, P35srj, Mrg1,  Cited2, Msg2

Immunogen

Recombinant protein corresponding to Mouse CITED2

Isotype IgG
Purity Affinity purification

Predicted MW.

28 kDa

Observed MW.

28 kDa

Uniprot ID

O35740, Q99MA1

 


 

Applications

 

Applications

WB

Species

Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

brain, heart

 


 

Background

 

CITED2, also named as P35srj, is a cAMP-responsive element-binding protein (CBP)/p300-transactivator, with an ED(Glu/Asp)-rich C-terminal domain that acts as an important modulator in the development of the heart .It is proposed to be a negative regulator of HIF-1α through its competitive binding to the CH1 domain of CBP/p300, which mediated signaling and to a decrease in HIF-1-responsive genes such as VEGF. In addition, it is also a co-activator of the transcriptional activity of the TFAP2 isoform, which is an extensively expressed nuclear protein with functions in embryogenesis, inflammation, and stress responses.

 


 

Images

 

Western blot analysis of CITED2 (GB111129) at dilution of 1: 1000
Lane 1: Mouse brain tissue lysate
Lane 2: Rat heart tissue lysate
Lane 3: Rat brain tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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