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Anti -ZAP70 Rabbit pAb

Cat. No. GB111128

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

ZAP70 rabbit polyclonal

Protein full name

Tyrosine-protein kinase ZAP-70

Synonyms

70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, Zap70, Srk, Zap-70

Immunogen

Recombinant protein corresponding to Mouse ZAP70

Isotype IgG
Purity Affinity purification

Predicted MW.

70 kDa

Observed MW.

70 kDa

Uniprot ID

P43403, P43404

 


 

Applications

 

Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

lymph nodes, thymus, spleen

 


 

Background

 

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells.

 


 

Images

 

Western blot analysis of ZAP70 (GB111128) at dilution of 1: 1000
Lane 1: Jurkat cell lysate
Lane 2: Mouse lymph nodes tissue lysate
Lane 3: Mouse thymus tissue lysate
Lane 4: Mouse spleen tissue lysate
Lane 5: Rat lymph nodes tissue lysate
Lane 6: Rat thymus tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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