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Anti -Rab11A Rabbit pAb

Cat. No. GB111127

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

Rab11A rabbit polyclonal

Protein full name

Ras-related protein Rab-11A

Synonyms

Rab-11, Rab11a, Rab11

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Rab11A

Isotype IgG
Purity Affinity purification

Predicted MW.

24 kDa

Observed MW.

24 kDa

Uniprot ID

P62491, P62492, P62494

 


 

Applications

 

Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

brain, spleen

 


 

Background

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. Rab11a and Rab11b are known markers for protein trafficking, sorting, and recycling in the endosomal pathway. The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, where they regulate membrane recycling back to the plasma membrane.

 


 

Images

 

Western blot analysis of Rab11A (GB111127) at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: MCF7 cell lysate
Lane 3: SH-SY5Y cell lysate
Lane 4: N2A cell lysate
Lane 5: PC12 cell lysate
Lane 6: Mouse brain tissue lysate
Lane 7: Mouse spleen tissue lysate
Lane 8: Rat brain tissue lysate
Lane 9: Rat spleen tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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