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Anti -TCPTP Rabbit pAb

Cat. No. GB111126

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

TCPTP rabbit polyclonal

Protein full name

Tyrosine-protein phosphatase non-receptor type 2

Synonyms

Protein-tyrosine phosphatase PTP-2, MPTP, Ptpn2, Ptpt

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TCPTP

Isotype IgG
Purity Affinity purification

Predicted MW.

47 kDa

Observed MW.

47 kDa

Uniprot ID

P17706, Q06180

 


 

Applications

 

Applications

WB

Species

Human, Mouse

Dilution

1: 500-1: 1000

Positive tissue

ovary

 


 

Background

 

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported.
 


 

Images

 

Western blot analysis of TCPTP (GB111126) at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: A549 cell lysate

Lane 3: K562 cell lysate

Lane 4: Mouse ovary tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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