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Anti -Hsp60 Mouse mAb

Cat. No. GB12243

Brand:Servicebio

Price:230

Specification: 100μl

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Product Information

 

Description

HSP60 mouse monoclonal

Protein full name

60 kDa heat shock protein, mitochondrial

Synonyms

HSP60, HSP-60, HuCHA60, CPN60, 60 KDa Chaperonin, P60 Lymphocyte Protein, Heat Shock Protein 60

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse HSP60

Isotype IgG
Purity Affinity purification
Subcellular location

Cytoplasm

Predicted MW.

60 kDa

Observed MW.

60 kDa

Uniprot ID

P10809P63039P63038

 


 

Applications

 

Applications

WB

IHC

Species

Human, Mouse, Rat

Human, Mouse, Rat

Dilution

1: 500-1: 1000

1: 1000-1: 2000

Positive tissue

Hela, HepG2, MCF7, NIH/3T3, PC12

colon, colon cancer, kidney

 


 

Background

 

Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60's bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix. Further studies have linked HSP60 to diabetes, stress response, cancer and certain types of immunological disorders.

 


 

Images

 

Western blot analysis of HSP60 (GB12243) at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: MCF7 cell lysate

Lane 4: NIH/3T3 cell lysate

Lane 5: PC12 cell lysate

   

Immunohistochemistry analysis of paraffin-embedded human colon using HSP60 (GB12243) at dilution of 1: 2000

   

IImmunohistochemistry analysis of paraffin-embedded human colon cancer using HSP60 (GB12243) at dilution of 1: 1000

   

Immunohistochemistry analysis of paraffin-embedded mouse kidney using HSP60 (GB12243) at dilution of 1: 2000

   

Immunohistochemistry analysis of paraffin-embedded rat kidney using HSP60 (GB12243) at dilution of 1: 2000
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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