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Anti -SIK1 Rabbit pAb

Cat. No. GB111034

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

Description

SIK1 rabbit polyclonal

Protein full name

Serine/threonine-protein kinase SIK1

Synonyms

HRT-20, Myocardial SNF1-like kinase, Serine/threonine-protein kinase SNF1-like kinase 1, Salt-inducible kinase 1, SIK1

Immunogen

Recombinant protein corresponding to Mouse SIK1

Isotype IgG
Purity Affinity purification

Predicted MW.

85 kDa

Observed MW.

90 kDa

Uniprot ID

Q60670Q9R1U5

 


 

Applications

 

Applications

WB

Species

Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

stomach, lung, ovary, heart, ovary

 


 

Background

 

SIK1(Salt-inducible kinase 1) is also named as SIK, SNF1LK and belongs to the CAMK Ser/Thr protein kinase family. It associates constitutively with the NK regulatory complex and is responsible for increases in its catalytic activity following small elevations in intracellular sodium concentrations. SIK1 is required for phosphorylation of class II HDACs and for expression of MEF2 target genes in myocytes. Defects in SIK1 may be associated with some cancers, such as breast cancers. Loss of SIK1 correlates with poor patient outcome in breast cancers.

 


 

Images

 

Western blot analysis of SIK1 (GB111034) at dilution of 1: 1000

Lane 1: L929 cell lysate

Lane 2: Mouse stomach tissue lysate

Lane 3: Mouse lung tissue lysate

Lane 4: Mouse ovary tissue lysate

Lane 5: Rat heart tissue lysate

Lane 6: Rat ovary tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

 

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