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Anti -Hsp60 Rabbit pAb

Cat. No. GB11243

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

HSP60 rabbit polyclonal

Protein full name

60 kDa heat shock protein, mitochondrial

Synonyms

HSP60, HSP-60, HuCHA60, CPN60, 60 KDa Chaperonin, P60 Lymphocyte Protein, Heat Shock Protein 60

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse HSP60 

Isotype IgG
Purity Affinity purification

Predicted MW.

60KDa

Observed MW.

60KDa

Subcellular location

Mitochondrion matrix

Uniprot ID

P10809P63039P63038

 


 

Applications

 

 

Applications

WB

IHC, IF

Species

Human, Mouse, Rat

Human, Mouse, Rat

Dilution

1:3000-1:10000

1:500-1:1000

Positive tissue

Spleen, brain, U87, U251, SH-5SY5Y, RGC-5

Colon, kidney

 


 

Background

 

 

Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60’s bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix. Further studies have linked HSP60 to diabetesstress response, cancer and certain types of immunological disorders.

   


 

Images

 

 

Western blot analysis of HSP60 (GB11243) at dilution of 1:5000.

Lane 1: U87 cell lysate

Lane 2: U251 cell lysate

Lane 3: SH-SY5Y cell lysate

Lane 4: RGC-5 cell lysate

Lane 5: Raw264.7 cell lysate

Lane 6: Mouse spleen tissue lysate

Lane 7: Mouse brain tissue lysate

Lane 8: Rat spleen tissue lysate

Lane 9: Rat brain tissue lysate

   

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Immunohistochemistry analysis of paraffin-embedded human colon using HSP60 (GB11243) at dilution of 1:1000

 

   

blob.png

Immunohistochemistry analysis of paraffin-embedded rat kidney using HSP60 (GB11243) at dilution of 1:1000

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.