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Anti -FOXP3 Rabbit pAb

Cat. No. GB11093-1

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

FOXP3 rabbit polyclonal

Protein full name

Forkhead box protein P3

Synonyms

FOXP3,AIID,DIETER,IPEX,JM2,PIDX,XPID, forkhead box P3

Immunogen

Recombinant protein corresponding to Mouse FOXP3

Isotype IgG
Purity Affinity purification
Predicted MW.

45-50KDa

Observed MW.

45-50KDa

Uniprot ID Q99JB6,Q9BZS1

 


 

Applications

 

 

Applications

WB

   
Species

Human, Rat, Mouse

   
Dilution 1:500-1:1000    
Positive tissue

PC3, inflammatory spleen, thymus gland

   

 


 

Background

 

 

FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body's own tissues.

   


 

Images

 

 

Western blot analysis of FOXP3 (GB11093-1) at dilution of 1:800.

Lane 1: MCF7 cell lysate

Lane 2: PC3 cell lysate

Lane 3: Mouse inflammatory spleen tissue lysate

Lane 4: Mouse thymus gland tissue lysate

Lane 5: Mouse spleen tissue lysate

Lane 6: Rat thymus gland tissue lysate

Lane 7: Rat inflammatory spleen tissue lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.