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Anti -FOXO3A Rabbit pAb

Cat. No. GB11092

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

FOXO3A rabbit polyclonal

Protein full name

Forkhead box protein O3

Synonyms

FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, forkhead box O3

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse FOXO3A
Isotype IgG
Purity Affinity purification
Predicted MW.

95KDa

Observed MW.

95KDa

Uniprot ID Q9WVH4

 


 

Applications

 

 

Applications

WB

   
Species

Rat

   
Dilution 1:500-1:1000    
Positive tissue

Heart, lung

   

 


 

Background

 

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

   


 

Images

 

 

Western blot analysis of FOXO3A (GB11092) at dilution of 1:750.

Lane 1: Rat heart tissue lysate

Lane 2: Rat lung tissue lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.