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Anti -Fas Ligand Rabbit pAb

Cat. No. GB11090-1

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Fas Ligand rabbit polyclonal

Protein full name

Tumor necrosis factor ligand superfamily member 6

Synonyms

ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse FASL

Isotype IgG
Purity Affinity purification
Subcellular location

Membrane, Single-pass type I membrane protein

Uniprot ID

P25446

 


 

Applications

 

 

Applications

IHC, IF

   
Species

Human, Mouse, Rat

   
Dilution

1:500-1:1000

   
Positive tissue

Appendix, spleen, thymus, liver

   

 


 

Background

 

 

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

     


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded human appendix  using FasL (GB11090-1) at dilution of 1:1000

   
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Immunohistochemistry analysis of paraffin-embedded mouse Immunized spleen using FasL (GB11090-1) at dilution of 1:1000

   
blob.png Immunohistochemistry analysis of paraffin-embedded mouse Immunized thymus using FasL (GB11090-1) at dilution of 1:1000
   
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Immunohistochemistry analysis of paraffin-embedded rat liver using FasL (GB11090-1) at dilution of 1:1000

   
blob.png

Immunohistochemistry analysis of paraffin-embedded rat spleen using FasL (GB11090-1) at dilution of 1:1000

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.