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Anti -Desmin Rabbit pAb

Cat. No. GB11081

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Desmin rabbit polyclonal

Protein full name

Desmin

Synonyms

DES, CSM1, CSM2, LGMD2R, desmin

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse desmin
Isotype IgG
Purity Affinity purification
Predicted MW. 54KDa
Observed MW. 55KDa
Subcellular location Cytoplasm, Cell membrane
Uniprot ID P31001,P48675

 


 

Applications

 

 

Applications

WB

IHC, IF

 
Species Mouse, Rat Mouse, Rat  
Dilution

1:1000-1:2000

1:1000-1:2000  
Positive tissue

Heart

Heart, skeletal muscle

 

 


 

Background

 

 

Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.

 


 

Images

 

 

Western blot analysis of Desmin (GB11081) at dilution of 1:1000.

Lane 1: Mouse heart tissue lysate

Lane 2: Mouse heart tissue lysate

Lane 3: Mouse heart tissue lysate

Lane 4: Rat heart tissue lysate

   

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Immunohistochemistry analysis of parafffin-embedded mouse heart using Desmin (GB11081) at dilution of 1:1800
   

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Immunohistochemistry analysis of parafffin-embedded rat skeletal muscle using Desmin (GB11081) at dilution of 1:1800

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.