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Anti -CD31 Rabbit pAb

Cat. No. GB11063-2

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

Description CD31 rabbit polyclonal
Protein full name Platelet endothelial cell adhesion molecule
Synonyms CD31 Antigen, EndoCAM, PECAM-1, GPIIA, PECA1
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse CD31 
Isotype IgG
Purity Affinity purification
Subcellular location Endothelium
Predicted MW. 83KDa
Observed MW. 90/130KDa
Uniprot ID P16284,Q08481,Q3SWT0

 


 

Applications

 

applications species dilution Positive tissue
WB Human,
Rat, Mouse
1:1000 Hela, HepG2, SW480, 293T, lung, kidney
IHC Human,
Rat, Mouse
1: 400-1: 1000 liver cancaer,  esophagus cancer, lung, heart, liver
IF Human,
Rat, Mouse
1:1000-1:2000 lung, heart, liver, brain,ovary

 


 

Background

 

Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation.

     


 

Images

 

blob.png

Western blot analysis of CD31 (GB11063-2) at dilution of 1:1000.

Lane 1:Hela cell lysate

Lane 2:HepG2 cell lysate

Lane 3:SW480 cell lysate

Lane 4:293T cell lysate

Lane 5:Mouse lung tissue lysate

Lane 6:Mouse kidney tissue lysate

Lane 7: Rat lung tissue lysate

Lane 8:Rat kidney tissue lysate

Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD31 (GB11063-2) at dilution of
1: 800
 

Immunohistochemistry analysis of paraffin-embedded human esophagus cancer using CD31 (GB11063-2) at dilution of 1: 800
 
 

Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using CD31 (GB11063-2) at dilution of 1: 800
 

Immunofluorescent analysis of paraformaldehyde-fixed mouse heart using CD31 (GB11063-2) at dilution of 1: 800
 

Immunofluorescent analysis of paraformaldehyde-fixed rat lung using CD31 (GB11063-2) at dilution of 1: 800
 

Immunofluorescent analysis of paraformaldehyde-fixed Rat heart using
CD31 (GB11063-2) at dilution of 1: 800
 

Immunohistochemistry analysis of paraffin-embedded rat liver using
CD31 (GB11063-2) at dilution of 1: 800
 

Immunohistochemistry analysis of paraffin-embedded mouse ovary using
CD31 (GB11063-2) at dilution of 1: 1000
 

Immunohistochemistry analysis of paraffin-embedded mouse heart using
CD31 (GB11063-2) at dilution of 1: 1000
 

Immunohistochemistry analysis of paraffin-embedded rat brain using
CD31 (GB11063-2) at dilution of 1: 1000
 

Immunohistochemistry analysis of paraffin-embedded rat lung using
CD31 (GB11063-2) at dilution of 1: 1000
 

Immunohistochemistry analysis of paraffin-embedded rat heart using
CD31 (GB11063-2) at dilution of 1: 1000
 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.