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Anti -Collagen I Rabbit pAb

Cat. No. GB11022-3

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Collagen I rabbit polyclonal

Protein full name

Collagen alpha-1(I) chain

Synonyms

COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain

Immunogen

Recombinant protein corresponding to Mouse COL1A1 

Isotype IgG
Purity Affinity purification
Subcellular location

Secreted

Uniprot ID

P11087,P02452,P02454

 


 

Applications

 

 

Applications IHC, IF
Species

Mouse, Rat

Dilution

1:800-1:1600

Positive tissue

Kidney, lung, colon

 


 

Background

 

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. 

     


 

Images

 

 

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Immunofluorescence analysis of paraffin-embedded mouse kidney using CollagenI(GB11022-3) at dilution of 1:1600

 

   

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Immunohistochemistry (antigen was repair with 0.4% pepsin for 20 min) analysis of paraffin-embedded mouse lung using CollagenI(GB11022-3) at dilution of 1:1000

   

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Immunofluorescence analysis of paraffin-embedded rat kidney using CollagenI(GB11022-3) at dilution of 1:1600

   

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Immunofluorescence (antigen was repair with 0.4% pepsin for 20 min) analysis of paraffin-embedded rat colon using collagenI(GB11022-3) at dilution of 1:1000

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.