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Anti -Bax Rabbit pAb

Cat. No. GB11007-1

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Bax rabbit polyclonal

Protein full name

Apoptosis regulator Bax

Synonyms

BCL2 Associated X Protein ,Bcl-2-Like Protein 4,BCL2L4,Bcl2-L-4

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bax

Isotype IgG
Purity Affinity purification
Subcellular location

Mitochondrion membrane. Cytoplasm

Uniprot ID

Q07812, Q07813, Q63690

 


 

Applications

 

 

Applications

IHC, IF

   
Species

Human, Mouse, Rat

   
Dilution

1:500-1:1500

   
Positive tissue

Stomach cancer, lung, colon

   

 


 

Background

 

 

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

            


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded Human stomach cancer using Bax (GB11007-1) at dilution of 1:1500

   
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Immunohistochemistry analysis of paraffin-embedded rat lung using Bax (GB11007-1) at dilution of 1:900

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.