Chinese | English  
Servicebio

TEL

+86 (0) 27 5111 3188

Polyclonals

  1. Home
  2. Products
  3. Primary antibodies
  4. Polyclonals
  5. Content

Anti -BAX Rabbit pAb

Cat. No. GB11007

Brand:Servicebio

Price:230.00

Specification: 100μlThis product is temporarily out of stock.

Download Attachment Files
Attachment Download Address: ×
/e/DownSys/DownSoft/?classid=19&id=1312&pathid=0

Product Information

 

 

Description Bax rabbit polyclonal
Protein full name Apoptosis regulator Bax
Synonyms BCL2 Associated X Protein ,Bcl-2-Like Protein 4,BCL2L4,Bcl2-L-4
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse Bax
Isotype IgG
Purity Affinity purification
Predicted MW.

21 kDa

Observed MW. 21 kDa
Uniprot ID Q07812Q07813Q63690

 


 

Applications

 

 

Applications WB
Species Human, Mouse, Rat
Dilution 1:1000
Positive tissue Hela, HepG2, colon cancer, liver cancer

 


 

Background

 

 

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

 


 

Images

 

 

blob.png

 

Western blot analysis of Bax (GB11007) at dilution of 1:1000.

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: Human colon cancer lysate

Lane 4: Human liver cancer lysate

Lane 5: Human breast cancer lysate

Lane 6: Human nasopharyngeal cancer tissue lysate

Lane 7: KB cell lysate

Lane 8: SP20 cell lysate

Lane 9: PC12 cell lysate

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.