Chinese | English  
Servicebio

TEL

+86 (0) 27 5111 3188

Polyclonals

  1. Home
  2. Products
  3. Primary antibodies
  4. Polyclonals
  5. Content

Anti -p38 Rabbit pAb

Cat. No. GB11005

Brand:Servicebio

Price:230.00

Specification: 100μl

Download Attachment Files
Attachment Download Address: ×
/e/DownSys/DownSoft/?classid=19&id=1311&pathid=0

Product Information

 

 

Description

P38 rabbit polyclonal

Protein full name Mitogen-activated protein kinase 14
Synonyms

MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2,PRKM14,PRKM15, RK, SAPK2A,p38,p38ALPHA, mitogen-activated protein kinase 14

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse P38 
Isotype IgG
Purity Affinity purification
Subcellular location Cytoplasm, Nucleus
Uniprot ID Q16539, P47811, P70618

 


 

Applications

 

 

Applications IHC, IF
Species Human, Mouse, Rat
Dilution 1:1000-1:2000
Positive tissue Lung cancer, lung, brain, kidney

 


 

Background

 

 

MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such asproliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response.

 


 

Images

 

 

blob.png

Immunohistochemistry analysis of paraffin-embedded human lung cancer using P38 (GB11005) at dilution of 1:1000.

   

blob.png

Immunohistochemistry analysis of paraffin-embedded rat lung using P38 (GB11005) at dilution of 1:1000.

 

   

blob.png

Immunohistochemistry analysis of paraffin-embedded rat brain using P38 (GB11005) at dilution of 1:1000.

   

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using P38 (GB11005) at dilution of 1:1000.

   

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse lung using P38 (GB11005) at dilution of 1:1000.

 

   

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse testis using P38 (GB11005) at dilution of 1:1000.

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.