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Anti–ERK1 (pT202/pY204) + ERK2 (pT185/pY187) Rabbit pAb

Cat. No. GB11004

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

ERK1 (pT202/pY204) + ERK2 (pT185/pY187) rabbit polyclonal

Protein full name Mitogen-activated protein kinase 1
Synonyms APK1, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK, mitogen-activated protein kinase 1
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse ERK2
Isotype

IgG

Purity Affinity purification
Predicted MW. 42/44 kDa
Observed MW.

42/44 kDa

Uniprot ID P63085Q63844

 


 

Applications

 

 

Applications WB
Species Mouse, Rat
Dilution 1:800
Positive tissue

Lung, kidney, NIH/3T3

 


 

Background

 

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

 


 

Images

 

 

Western blot analysis of Erk1 (pT202/pY204) + Erk2 (pT185/pY187)  (GB11004) at dilution of 1:800.

Lane 1: Hela cell lysate

Lane 2: HUVEC cell lysate

Lane 3-5: NIH/3T3 cell lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Mouse kidney tissue lysate

Lane 8: Rat lung tissue lysate

Lane 9: Rat kidney tissue lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.