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Anti -Integrin beta 1 Rabbit pAb

Cat. No. GB11537

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description Integrin beta 1 rabbit polyclonal
Protein full name

Integrin beta-1

Synonyms

ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, integrin subunit beta 1

Immunogen

Recombinant protein corresponding to Mouse Integrin beta 1

Isotype IgG
Purity Affinity purification

Predicted MW.

88 kDa

Observed MW.

130 kDa

Uniprot ID

P09055, P49134

 


 

Applications

 

 

Applications

WB

 
Species

Mouse, Rat

 
Dilution

1:1000

 
Positive tissue lung, kidney  

 


 

Background

 

 

Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor. This integrin associates with integrins alpha 1 and 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha 3 to form integrin receptors for netrin 1 and reelin. Integrin beta 1 is expressed as at least four different isoforms. In cardiac muscle and skeletal muscle, the integrin beta-1D isoform is specifically expressed, and localizes to costameres, where it aids in the lateral force transmission from the Z-discs to the extracellular matrix. Abnormal levels of integrin beta-1D have been found in limb girdle muscular dystrophy and polyneuropathy.        

     


 

Images

 

 

blob.png  

Western blot analysis of Integrin beta 1 (GB11537) at dilution of 1:1000.

Lane 1: Mouse lung tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Rat lung tissue lysate

Lane 4: Rat kidney tissue lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.