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Anti -Myelin Basic Protein Rabbit pAb

Cat. No. GB11226

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Myelin Basic Protein rabbit polyclonal

Protein full name

Myelin Basic Protein

Synonyms

MBP, entrez:4155, myelin basic protein

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein

Isotype IgG
Purity Affinity purification
Predicted MW.

17-22KDa

Observed MW.

17-20KDa

Subcellular location

Myelin membrane, Cytoplasmic side of myelin

Uniprot ID

P04370P02688

 


 

Applications

 

 

Applications

WB

IHC, IF

 
Species

Mouse, Rat

Mouse, Rat

 
Dilution

1:500-1:1000

1:300-1:600

 
Positive tissue

Brain

Brain

 

 


 

Background

 

The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.

   


 

Images

 

 

Western blot analysis of Myelin Basic Protein (GB11226) at dilution of 1:1000.

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse hippocampus tissue lysate

Lane 3: Mouse cerebellum tissue lysate

Lane 4: Rat brain tissue lysate

Lane 5: Rat hippocampus tissue lysate

Lane 6: Rat cerebellum tissue lysate

   

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using Myelin Basic Protein (GB11226) at dilution of 1:600

   

blob.png

Immunohistochemistry analysis of paraffin-embedded rat brain using Myelin Basic Protein (GB11226) at dilution of 1:600

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.