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Neural Cell Marker

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Anti-TAU Rabbit pAb

Cat. No. GB11178

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

Description Tau rabbit polyclonal
Protein full name Microtubule-associated protein tau
Synonyms MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse Tau 
Isotype IgG
Predicted MW. 79 KDa
Observed MW. 40-70KDa
Purity Affinity purification
Subcellular location Cytoplasm,Cell membrane,Cell projection
Uniprot ID P10637, P19332P10636

 


 

Applications

 

applications species dilution Positive tissue
WB Human, Mouse,Rat 1:1000 Brain
IHC,IF Human, Mouse,Rat 1:100-1:500 Brain

 


 

Background

 

 

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    


 

Images

 

 

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Western blot analysis of Tau(GB11178) at dilution of 1:1000

Lane 1: Mouse brain tissue lysate

Lane 2: Rat brain tissue lysate

 

   

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Immunohistochemistry analysis of paraffin-embedded rat brain using Tau(GB11178) at dilution of 1:100

 

   

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Immunohistochemistry analysis of paraffin-embedded human brain using Tau(GB11178) at dilution of 1:100

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

 

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