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Anti -Choline Acetyltransferase Rabbit pAb

Cat. No. GB11070

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Choline Acetyltransferase rabbit polyclonal

Protein full name

Choline O-acetyltransferase

Synonyms

CHAT, CHOACTASE, CMS1A, CMS1A2, CMS6, choline O-acetyltransferase

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CHAT

Isotype IgG
Purity Affinity purification
Subcellular location

Cytoplasm, Cytosol, Nucleus, Presynapse

Uniprot ID Q03059P32738

 


 

Applications

 

 

Applications

IHC, IF

   
Species Mouse, Rat    
Dilution 1:100-1:500    
Positive tissue

brain

   

 


 

Background

 

 

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

     


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded mouse brain using ChAT(GB11070) at dilution of 1:500
   

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Immunohistochemistry analysis of paraffin-embedded mouse brain using ChAT(GB11070) at dilution of 1:100

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.