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Anti -GABA A Receptor alpha 1 Rabbit pAb

Cat. No. GB11561

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

GABA A Receptor alpha 1 rabbit polyclonal

Protein full name

Gamma-aminobutyric acid receptor subunit alpha-1

Synonyms

GABRA1, ECA4, EIEE19, EJM, EJM5, gamma-aminobutyric acid type A receptor alpha1 subunit
Immunogen Recombinant protein corresponding to Mouse GABA A Receptor alpha 1
Isotype IgG
Purity Affinity purification

Predicted MW.

52 kDa

Observed MW.

52 kDa

Uniprot ID

P14867

 


 

Applications

 

 

Applications WB    
Species Human    
Dilution 1:500-1:1000    
Positive tissue

U87, U251, SH-SY5Y

   

 


 

Background

 

 

Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA1 receptor is the specific target of the z-drug class of nonbenzodiazepine hypnotic agents and is responsible for their hypnotic and hallucinogenic effects.        

     


 

Images

 

 

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Western blot analysis of GABA A Receptor alpha 1 (GB11561) at dilution of 1:800.
 

Lane 1: U87 cell lysate
 

Lane 2: U251 cell lysate
 

Lane 3: SH-SY5Y cell lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.