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Anti -S100 beta Rabbit pAb

Cat. No. GB11359

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

S100 beta rabbit polyclonal

Protein full name

Protein S100-B

Synonyms

S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse S100B
Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus,Cytoplasm

Uniprot ID P50114P04631P04271

 


 

Applications

 

 

Applications

IHC, IF

   
Species

Mouse, Rat

   
Dilution

1:500-1:1000

   
Positive tissue brain    

 


 

Background

 

 

S100B is glial-specific and is expressed primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS it acts as a neurotrophic factor and neuronal survival protein. In the adult organism it is usually elevated due to nervous system damage, which makes it a potential clinical marker.

            


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded mouse brain using S100B (GB11359) at dilution of 1:1000.

 

   
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Immunohistochemistry analysis of paraffin-embedded rat brain using S100B (GB11359) at dilution of 1:500.

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.