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MEK1 Mouse Monoclonal

Cat. No. GB12304

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

Description MEK1 mouse monoclonal
Protein full name Dual specificity mitogen-activated protein kinase kinase 1
Synonyms MAP2K1, CFC3, MAPKK1, MEK1, MKK1,
PRKMK1, mitogen-activated protein kinase 1
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse MEK1
Isotype IgG
Purity Affinity purification
Predicted MW. 43 kDa
Observed MW. 45 kDa
Uniprot ID Q02750, P31938, Q01986

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Human, Mouse,Rat 1: 1000-1: 2000 lung, kidney, brain

 


 

Background  

 

The protein is a member of the dual-specificity protein kinase family that acts as amitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon activation by a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.    

     


 

Images

 

 

2.jpg  

Western blot analysis of MEK1(GB12304) at dilution of 1: 1000

Lane 1: HUVEC cell lysate

Lane 2: A549 cell lysate

Lane 3: HepG2 cell lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Mouse kidney tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat lung tissue lysate

Lane 8: Rat kidney tissue lysate

Lane 9: Rat brain tissue lysate

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.