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Anti-Desmin Mouse mAb

Cat. No. GB12081

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Desmin mouse monoclonal

Protein full name Desmin

Synonyms

DES, CSM1, CSM2, LGMD2R, desmin
Immunogen

Recombinant protein corresponding to Mouse desmin

Isotype IgG
Purity Affinity purification
Predicted MW.

54 kDa

Observed MW.

55 kDa

Subcellular location

Cytoplasm, Cell membrane

Uniprot ID P31001P48675

 


 

Applications

 

 

Applications

WB

IHC, IF

 
Species

Mouse, Rat

Mouse, Rat

 
Dilution

1:1000-1:2000

1:200-1:1000

 
Positive tissue

Heart, C2C12 cell

Heart, skeletal muscle

 

 


 

Background

 

 

Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.

     


 

Images

 

 

blob.png

Western blot analysis of Desmin (GB12081) at dilution of 1:1000.

Lane 1: C2C12 cell lysate

Lane 2: Hela cell lysate

Lane 3: Raw264.7 cell lysate

Lane 4: Mouse heart tissue lysate

Lane 5: Mouse spleen tissue lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Rat heart tissue lysate

   
blob.png

Immunohistochemistry analysis of parafffin-embedded mouse heart using Desmin (GB12081) at dilution of 1:500

   
blob.png

Immunohistochemistry analysis of parafffin-embedded rat skeletal muscle using Desmin (GB12081) at dilution of 1:500

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.