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Anti -Cytochrome C Mouse mAb

Cat. No. GB12080

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

Cytochrome C mouse monoclonal

Protein full name

Cytochrome c

Synonyms

CYCS, CYC, HCS, THC4, cytochrome c, somatic, Cytochrome c, cyt c

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c

Isotype IgG
Purity Affinity purification

Predicted MW.

12 kDa

Observed MW.

14 KDa

Subcellular location

Mitochondrion intermembrane space

Uniprot ID

P99999P62898P62897

 


 

Applications

 

 

Applications

WB

IHC

IF

Species

Mouse, Rat

Human, Rat

Human, Rat

Dilution

1: 500-1: 1000

1: 500-1: 1000

1: 250-1: 500

Positive tissue

heart

stomach, heart 

stomach, heart 

 


 

Background

 

 

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.         

     


 

Images

 

 

内页.jpg  

Western blot analysis of Cytochrome c (GB12080) at dilution of 1: 1000.

Lane 1: Mouse heart tissue lysate

Lane 2: Mouse heart tissue lysate

Lane 3: Rat heart tissue lysate

Lane 4: Rat heart tissue lysate

     
image.png  

Immunohistochemistry analysis of paraffin-embedded human stomach using Cytochrome c (GB12080) at dilution of 1: 1000

     
image.png  

Immunofluorescence analysis of paraffin-embedded rat heart using Cytochrome c (GB12080) at dilution of 1: 1000

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.