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Anti -c-Fos Mouse mAb

Cat. No. GB12069

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

c-Fos mouse monoclonal

Protein full name

Proto-oncogene c-Fos

Synonyms

FOS, AP-1, C-p55, Fos proto-oncogene, AP-1 transcription factor subunit

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse c-FOS

Isotype IgG
Purity Affinity purification

Predicted MW.

62KDa

Observed MW.

62KDa

Subcellular location

Nucleus, Endoplasmic reticulum, Cytoplasm

Uniprot ID

P01100P01101P12841

 


 

Applications

 

 

Applications

WB

IHC IF
Species

Human, Mouse, Rat

Human, Mouse, Rat Human, Mouse, Rat
Dilution

1:500-1:2000

1:500-1:2000 1:200-1:1000
Positive tissue

HepG2, jurkat, colon cancer, lung

Gallbladder, brain brain

 


 

Background

 

 

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

 


 

Images

 

 

image.png  

Western blot analysis of c-FOS (GB12069) at dilution of 1:1000.

Lane 1: HepG2 cell lysate

Lane 2: Jurkat cell lysate

Lane 3: Human colon cancer tissue lysate

Lane 4: Mouse lung tissue lysate

     
image.png  

Immunohistochemistry analysis of paraffin-embedded human gallbladder using c-FOS (GB12069) at dilution of 1:2000

     
image.png  

Immunohistochemistry analysis of paraffin-embedded rat brain using c-FOS (GB12069) at dilution of 1:2000

     
image.png  

Immunohistochemistry analysis of paraffin-embedded mouse brain using c-FOS (GB12069) at dilution of 1:2000

     
image.png  

Immunofluorescence analysis of paraffin-embedded rat brain using c-FOS (GB12069) at dilution of 1:1000

     
image.png  

Immunofluorescence analysis of paraffin-embedded mouse brain using c-FOS (GB12069) at dilution of 1:1000

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.