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Anti -beta Catenin Mouse mAb

Cat. No. GB12015

Brand:Servicebio

Price:230.00

Specification: 100μl

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Product Information

 

 

Description

beta Catenin mouse monoclonal

Protein full name Catenin beta-1

Synonyms

CTNNB1, CTNNB, MRD19, armadillo, catenin beta 1
Immunogen Recombinant protein corresponding to Mouse β-catenin 
Isotype IgG
Purity Affinity purification
Predicted MW. 92 kDa
Observed MW. 92 kDa
Subcellular location

Cytoplasm, Nucleus, Cell junction, Cell membrane

Uniprot ID P35222Q02248Q9WU82

 


 

Applications

 

 

Applications

WB

IHC, IF

 
Species

Mouse, Rat

Human, Mouse, Rat

 
Dilution

1:500-1:1000

1:100-1:500

 
Positive tissue

Lung, kidney

stomach  

 


 

Background

 

 

β-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to γ-catenin, also known as plakoglobin. Beta-catenin is widely expressed in many tissues. In cardiac muscle, beta-catenin localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocytes.

    


 

Images

 

 

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Western blot analysis of β-catenin (GB12015) at dilution of 1:1000.

Lane 1: Mouse lung tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Rat kidney tissue lysate

   
blob.png

Immunohistochemistry analysis of paraffin-embedded mouse stomach using β-catenin (GB12015)at dilution of 1:200

 

   
blob.png

Immunohistochemistry analysis of paraffin-embedded rat stomach using β-catenin (GB12015)at dilution of 1:200

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.