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Anti -CD5L/CT-2 Rabbit pAb for Apoptosis Western Blot Antibodies

Specification: 100uL
  • GB112614
  • Servicebio
  • Servicebio

Description

Product Information


Description

CD5L/CT-2 rabbit polyclonal

Protein full name

CD5 antigen-like

Synonyms

Apoptosis inhibitor expressed by macrophages, mAIM, Apoptosis inhibitory 6, SP-alpha, Cd5l, Aim, Api6

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD5L/CT-2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

39 kDa

Observed MW.

46 kDa

Uniprot ID

Q9QWK4




Applications


Applications

Species

Dilution

Positive Tissue

WB

Rat

1: 700-1: 1000

spleen, thymus




Background


CD5L is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that CD5L functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. CD5L was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant CD5L significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that CD5L functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection. Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues.




Images


图片 1.png

Western blot analysis of CD5L (GB112614) at dilution of 1: 1000

Lane 1: Rat spleen tissue lysate

Lane 2: Rat thymus tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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