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Anti -DLGAP1 Rabbit pAb Polyclonal antibody For WB

Specification: 100uL
  • GB112619
  • Servicebio
  • Servicebio

Description

Product Information


Description

DLGAP1 rabbit polyclonal

Protein full name

Disks large-associated protein 1

Synonyms

DAP-1, Guanylate kinase-associated protein, PSD-95/SAP90-binding protein 1, SAP90/PSD-95-associated protein 1, SAPAP1, Dlgap1, Gkap, Kiaa4162

Immunogen

Recombinant protein corresponding to

Mouse DLGAP1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

110 kDa

Observed MW.

110 kDa

Uniprot ID

Q9D415, P97836




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, cerebellum




Background


Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-a, DAP-1-b, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP, through the guanylate kinase domain. GKAP is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. GKAP is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.




Images


图片 1.png

Western blot analysis of DLGAP1 (GB112619) at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse cerebellum tissue lysate

Lane 3: Rat brain tissue lysate

Lane 4: Rat cerebellum tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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