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Anti -NDP Rabbit pAb Western Blot Antibodies

Specification: 100uL
  • GB112642
  • Servicebio
  • Servicebio

Description

Product Information


Description

NDP rabbit polyclonal

Protein full name

Norrin

Synonyms

Norrie disease protein homolog, Ndp, Ndph, FEVR, EVR2, X linked exudative vitreoretinopathy 2 protein

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse NDP

Isotype

IgG

Purity

Affinity purification

Predicted MW.

15 kDa

Observed MW.

15 kDa

Uniprot ID

P48744




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, testis, liver




Background


NDP, also named as EVR2, ND and Norrin, is a secreted regulatory protein that remains tightly associated with the extracellular matrix. Mutations in the NDP gene are associated with the Norrie disease. Signaling induced by the protein NDP regulates vascular development of vertebrate retina and controls important blood vessels in the ear. It binds with high affinity to Frizzled 4, and Frizzled 4 knockout mice exhibit abnormal vascular development of the retina.




Images


图片 1.png

Western blot analysis of NDP (GB112642) 

at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse testis tissue lysate

Lane 3: Mouse liver tissue lysate

Lane 4: Rat testis tissue lysate

Lane 5: Rat liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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