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Anti -DTYMK Rabbit pAb Western Blot Antibodies RNA synthesis related

Specification: 100uL
  • GB112644
  • Servicebio
  • Servicebio

Description

Product Information


Description

DTYMK rabbit polyclonal

Protein full name

Thymidylate kinase

Synonyms

dTMP kinase, Dtymk, Tmk, CDC8, TMPK

Immunogen

Recombinant protein corresponding to

Mouse DTYMK

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

P97930




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 200-1: 400

kidney




Background


DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.




Images


Immunohistochemistry analysis of paraffin-embedded mouse kidney using 

DTYMK (GB112644) at dilution of 1: 400

Immunohistochemistry analysis of paraffin-embedded rat kidney using 

DTYMK (GB112644) at dilution of 1: 400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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