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Anti -POLR1B Rabbit PAb for Western Blot RNA Synthesis Related Antibody

Specification: 100uL
  • GB112646
  • Servicebio
  • Servicebio

Description

Product Information


Description

POLR1B rabbit polyclonal

Protein full name

DNA-directed RNA polymerase I subunit RPA2

Synonyms

RNA polymerase I subunit 2, DNA-directed RNA polymerase I 135 kDa polypeptide, RPA135, Polr1b, Rpa2, Rpo1-2

Immunogen

Recombinant protein corresponding to

Mouse POLR1B

Isotype

IgG

Purity

Affinity purification

Predicted MW.

128 kDa

Observed MW.

128 kDa

Uniprot ID

Q9H9Y6, P70700




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 1000-1: 2000

K562, HepG2, A431, C2C12, NIH3T3




Background


DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.




Images


图片 1.png

Western blot analysis of POLR1B (GB112646) at dilution of 1: 2000

Lane 1: K562 cell lysate

Lane 2: HepG2 cell lysate

Lane 3: A431 cell lysate

Lane 4: C2C12 cell lysate

Lane 5: NIH3T3 cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

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