PHONE

+86(027) 5111 3188

Share to:

Anti -UAP1L1 Rabbit pAb for Western Blot Antibody

Specification: 100uL
  • GB112664
  • Servicebio
  • Servicebio

Description

Product Information


Description

UAP1L1 rabbit polyclonal

Protein full name

UDP-N-acetylhexosamine pyrophosphorylase-like protein 1

Synonyms

Uap1l1, UDP N acteylglucosamine pyrophosphorylase 1 like 1

Immunogen

Recombinant protein corresponding to

Mouse UAP1L1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

57 kDa

Observed MW.

57 kDa

Uniprot ID

Q3TW96




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 2000-1: 4000

pancreas, kidney, skin




Background


UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.




Images


图片 1.png

Western blot analysis of UAP1L1 (GB112664) at dilution of 1: 4000

Lane 1: Mouse pancreas tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Mouse skin tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.