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GB112174 Anti -UCP1 Thermogenin Slc25a7 Rabbit Polyclonal Antibody for WB IHC

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse UCP1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112174
  • Servicebio

Description

Product Information


Description

UCP1 rabbit polyclonal

Protein full name

Mitochondrial brown fat uncoupling protein 1

Synonyms

UCP1, Solute carrier family 25 member 7, Thermogenin, Slc25a7

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse UCP1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Mitochondrion

Predicted MW.

33 kDa

Observed MW.

33 kDa

Uniprot ID

P12242, P04633




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brown fat

IHC

Mouse, Rat

1: 200-1: 400

brown fat




Background


UCP-1 (Mitochondrial uncoupling protein 1), is a mitochondrial transporter protein that creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. It has been identified a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. UCP-1 expression is usually restricted to brown adipose when induced by cold exposure and thyroid hormone.




Images


Western blot analysis of UCP1 (GB112174) 

at dilution of 1: 1000

Lane 1: Mouse brown fat tissue lysate

Lane 2: Mouse brown fat tissue lysate

Lane 3: Rat brown fat tissue lysate

Lane 4: Rat brown fat tissue lysate


Immunohistochemistry analysis of paraffin-embedded mouse brown fat using 

UCP1 (GB112174) at dilution of 1: 400

Immunofluorescent analysis of paraformaldehyde-fixed rat brown fat using 

UCP1 (GB112174) at dilution of 1: 400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer(G2025).

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