+86(027) 5111 3188

Share to:

Anti -Integrin beta 3 Rabbit pAb for western blot IHC Primary antibody

Specification: 100uL
  • GB112253
  • Servicebio
  • Servicebio


Product Information


Integrin beta 3 rabbit polyclonal

Protein full name

Integrin beta-3


Platelet membrane glycoprotein IIIa, GPIIIa, CD61, ITGB3, GP3A


KLH conjugated Synthetic peptide

corresponding to Human Integrin beta 3




Affinity purification

Subcellular location

Cell membrane

Predicted MW.

87 kDa

Observed MW.

100 kDa

Uniprot ID

P05106, O54890, Q8R2H2





Positive Tissue


Human, Mouse, Rat

1: 500-1: 1000

spleen, thymus, lung


Mouse, Rat

1: 1000-1: 2000

spleen, bone marrow


Integrin beta-3, also named as CD61 and GPIIIa, is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin beta-3 recognize the sequence R-G-D in a wide array of ligands and the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen which leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. 


Western blot analysis of Integrin beta 3 (GB112253) at dilution of 1: 1000

Lane 1: HUVEC cell lysate

Lane 2: U87 cell lysate

Lane 3: C2C12 cell lysate

Lane 4: HeLa cell lysate

Lane 5: Mouse spleen tissue lysate

Lane 6: Mouse thymus tissue lysate

Lane 7: Mouse lung tissue lysate

Lane 8: Rat thymus tissue lysate

Immunohistochemistry analysis of paraffin-embedded mouse bone marrow  using Integrin beta 3 (GB112253) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat bone marrow using 

Integrin beta 3 (GB112253) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded mouse spleen using 

Integrin beta 3 (GB112253) at dilution of 1: 2000


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 10Slice 13Slice 14Slice 12

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.