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GB12338 Anti -PD1 Mouse Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse PD1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12338
  • Servicebio

Description

Product Information


Description

PD1 mouse monoclonal

Protein full name

Programmed cell death protein 1

Synonyms

Protein PD-1, mPD-1, CD279, Pdcd1, Pd1, SLEB2, Systemic lupus erythematosus susceptibility 2, hSLE1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse PD1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

Q15116




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 800-1: 1600

tonsil




Background


Programmed cell death 1 (PD-1, also known as CD279) is an immunoinhibitory receptor that belongs to the CD28/CTLA-4 subfamily of the Ig superfamily. It is a 288 amino acid (aa) type I transmembrane protein composed of one Ig superfamily domain, a stalk, a transmembrane domain, and an intracellular domain containing an immunoreceptor tyrosine-based inhibitory motif (ITIM) as well as an immunoreceptor tyrosine-based switch motif (ITSM) . PD-1 is expressed during thymic development and is induced in a variety of hematopoietic cells in the periphery by antigen receptor signaling and cytokines. 




Images


图片 1.png

Immunohistochemistry analysis of paraffin-embedded human tonsil using 

PD1 (GB12338) at dilution of 1: 1600




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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