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GB112525 Anti -TYK2 Tyrosine kinase 2 JTK1 Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse TYK2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112525
  • Servicebio

Description

Product Information


Description

TYK2 rabbit polyclonal

Protein full name

Non-receptor tyrosine-protein kinase TYK2

Synonyms

Tyk2, JTK1, Protein Tyrosine Kinase 2, Tyrosine kinase 2

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse TYK2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoskeleton, Cytoplasm

Uniprot ID

Q9R117




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 400-1: 800

liver, spleen, kidney




Background


This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.




Images


Immunohistochemistry analysis of paraffin-embedded mouse liver using 

TYK2 (GB112525) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded rat liver using 

TYK2 (GB112525) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded mouse spleen using 

TYK2 (GB112525) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded rat spleen using 

TYK2 (GB112525) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded rat kidney using 

TYK2 (GB112525) at dilution of 1: 800




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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