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GB112527 Anti -V2R AVPR V2 Avpr2 Rabbit Polyclonal Antibody for IHC

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse V2R
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112527
  • Servicebio

Description

Product Information


Description

V2R rabbit polyclonal

Protein full name

Vasopressin V2 receptor

Synonyms

V2R, AVPR V2, Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor, Avpr2

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse V2R

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

P30518, O88721, Q00788




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 600-1: 1200

kidney, lung




Background


This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. 




Images



Immunohistochemistry analysis of paraffin-embedded human kidney using 

AVPR2 (GB112527) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded rat kidney using 

AVPR2 (GB112527) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded mouse lung using 

AVPR2 (GB112527) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded rat lung using 

AVPR2 (GB112527) at dilution of 1: 1200




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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